Kentucky’s series record 18–2. Scores list Kentucky first.
| Date | Game | Result | Score | Notes |
|---|---|---|---|---|
| Nov 17, 1962 | Xavier at Kentucky | L | 9–14 | — |
| Nov 18, 1961 | Xavier at Kentucky | W | 9–0 | — |
| Nov 12, 1960 | Xavier at Kentucky | W | 49–0 | — |
| Nov 14, 1959 | Xavier at Kentucky | W | 41–0 | — |
| Nov 15, 1958 | Xavier at Kentucky | W | 20–6 | — |
| Nov 16, 1957 | Xavier at Kentucky | W | 27–0 | — |
| Nov 17, 1956 | Xavier at Kentucky | W | 33–0 | — |
| Nov 5, 1949 | Kentucky at Xavier | W | 21–7 | Cincinnati |
| Sept 25, 1948 | Xavier at Kentucky | W | 48–7 | — |
| Oct 4, 1947 | Kentucky at Xavier | W | 20–7 | Cincinnati |
| Oct 5, 1946 | Xavier at Kentucky | W | 70–0 | — |
| Sept 25, 1942 | Kentucky at Xavier | W | 35–19 | Cincinnati |
| Oct 18, 1941 | Kentucky at Xavier | W | 21–6 | Cincinnati |
| Sept 27, 1940 | Kentucky at Xavier | W | 13–0 | Cincinnati |
| Oct 28, 1939 | Kentucky at Xavier | W | 21–0 | Cincinnati |
| Oct 22, 1938 | Kentucky at Xavier | L | 7–26 | Cincinnati |
| Oct 2, 1937 | Kentucky at Xavier | W | 6–0 | Cincinnati |
| Sept 25, 1936 | Kentucky at Xavier | W | 21–0 | Cincinnati |
| Sept 27, 1935 | Kentucky at Xavier | W | 21–7 | Cincinnati |
| Oct 3, 1903 | Xavier at Kentucky | W | 21–0 | — |
Game results come from the Kentucky football season archive. Box scores are linked where a game-specific source was verified.