Head Coach: John J. Tigert
Record: 6–1–1
SEC Record: Not an SEC member
| Date | Opponent | Location | Score (UK first) |
|---|---|---|---|
| Oct 2 | Butler | Stoll Field Lexington | 33–0 |
| Oct 9 | Earlham | Stoll Field Lexington | 54–13 |
| Oct 16 | Mississippi A&M | New Athletic Field Starkville | 0–12 |
| Oct 23 | Sewanee | Stoll Field Lexington | 7–7 |
| Oct 30 | Cincinnati | Stoll Field Lexington | 27–6 |
| Nov 6 | Louisville | Eclipse Park Louisville | 15–0 |
| Nov 13 | Purdue | Stoll Field Lexington | 7–0 |
| Nov 25 | Tennessee | Stoll Field Lexington | 6–0 |
Source: UK Athletics’ 2024 Football Fact & Record Book, all-time results. Scores follow the historical listing.