Head Coach: Edwin Sweetland
Record: 7–2
SEC Record: Not an SEC member
| Date | Opponent | Location | Score (UK first) |
|---|---|---|---|
| Sept 24 | Ohio U. | Stoll Field Lexington | 12–0 |
| Oct 1 | Maryville Col. | Stoll Field Lexington | 12–5 |
| Oct 8 | North Carolina | Stoll Field Lexington | 11–0 |
| Oct 15 | Ky. Wesleyan | Stadium unverified Winchester | 42–0 |
| Oct 22 | Georgetown | Stoll Field Lexington | 37–0 |
| Oct 29 | Tulane | Stoll Field Lexington | 10–3 |
| Nov 5 | Tennessee | Waite Field Knoxville | 10–0 |
| Nov 12 | St. Louis | Sportsman's Park St. Louis | 0–9 |
| Nov 24 | Centre College | Stoll Field Lexington | 6–12 |
Source: UK Athletics’ 2024 Football Fact & Record Book, all-time results. Scores follow the historical listing.