Kentucky’s series record 2–2. Scores list Kentucky first.
| Date | Game | Result | Score | Notes |
|---|---|---|---|---|
| Oct 25, 1947 | Kentucky at Michigan State | W | 7–6 | E. Lansing |
| Nov 2, 1946 | Michigan State at Kentucky | W | 39–14 | — |
| Oct 6, 1945 | Kentucky at Michigan State | L | 6–7 | E. Lansing |
| Oct 7, 1944 | Michigan State at Kentucky | L | 0–2 | — |
Game results come from the Kentucky football season archive. Box scores are linked where a game-specific source was verified.